Basic Information
ID: ALA2400563
Type: Binding
Description: Inhibition of p-gp in human KB/VCR cells assessed as potentiation of 1 uM docetaxel-induced cytotoxicity at 5 uM after 72 hrs by MTT assay
Organism: Homo sapiens
Cell type: KB/VCR
Activity Charts
Bioactivity
Activity Types for Assay ALA2400563
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.74 | 6.50 | 6.50 |
| 553.87 | 6.76 | 6.76 |
| 526.81 | 5.72 | 5.72 |
| 526.81 | 5.72 | 5.72 |
| 526.81 | 5.72 | 5.72 |
| 541.82 | 6.66 | 6.66 |
| 525.82 | 6.32 | 6.32 |
| 539.85 | 6.89 | 6.89 |
| 555.84 | 6.33 | 6.33 |
| 543.81 | 6.46 | 6.46 |
| 560.26 | 6.98 | 6.98 |
| 585.87 | 6.34 | 6.34 |
| 539.85 | 6.37 | 6.37 |
| 574.29 | 7.02 | 7.02 |
| 584.84 | 6.27 | 6.27 |
| 599.90 | 6.38 | 6.38 |
| 583.85 | 6.10 | 6.10 |
| 449.72 | 4.75 | 4.75 |
| 463.75 | 5.14 | 5.14 |
| 477.77 | 5.53 | 5.53 |
| 477.77 | 5.53 | 5.53 |
| 491.80 | 5.92 | 5.92 |
| 475.76 | 5.29 | 5.29 |
| 543.84 | 5.41 | 5.41 |
| 547.87 | 4.03 | 4.03 |
| 493.77 | 4.51 | 4.51 |