Assay Report Card

Basic Information

ID: ALA2401435

Type: Functional

Description: Antioxidant activity in Leber's optic atrophy disease patient GM10744 cells assessed as suppression of diethyl maleate-induced ROS generation at 0.025 to 2.5 uM preincubated for 18 hrs prior to diethyl maleate-challenge measured after 1 hr by FACS flow cytometric analysis in presence of DCFH-DA

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
322.454.494.49
338.443.463.46
309.453.213.21
293.464.244.24
377.626.586.58