Basic Information
ID: ALA2405605
Type: Binding
Description: Inhibition of 11beta-HSD1 in rat testis microsomes using [3H]-11-DHC as substrate assessed as formation of CORT after 60 to 90 mins by radiometric analysis
Organism: Rattus norvegicus
Tissue: Testis
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2405605
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.39 | 3.85 | 3.85 |
| 326.35 | 3.41 | 3.41 |
| 534.65 | 6.73 | 6.73 |
| 432.15 | 6.43 | 6.43 |
| 392.09 | 5.51 | 5.51 |
| 296.32 | 4.79 | 4.79 |
| 418.13 | 6.04 | 6.04 |
| 310.34 | 5.18 | 5.18 |
| 418.13 | 6.04 | 6.04 |