Assay Report Card

Basic Information

ID: ALA2405842

Type: ADME

Description: Inhibition of CYP2C19 in human liver microsomes assessed as (S)-Mephenytoin hydroxylation to 4'-Hydroxymephenytoin after 30 mins by LC-MS/MS analysis

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
492.596.086.08
661.815.665.66