Assay Report Card

Basic Information

ID: ALA2405915

Type: Binding

Description: Inhibition of mouse 11beta-HSD1 expressed in HEK293 cell microsomes assessed as inhibition of [3H]cortisone conversion to [3H]cortisol at 1 uM by scintillation proximity assay

Organism: Mus musculus

Cell type: HEK293

Subcellular Fraction: Microsome

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
470.696.416.41
288.484.954.95
302.465.045.04
517.465.615.61
481.634.914.91
447.573.463.46
460.604.694.69
304.434.054.05
318.464.014.01
320.454.994.99
336.473.063.06
350.462.192.19
332.443.193.19
290.475.935.93
299.465.045.04
399.605.995.99
410.586.676.67
450.716.986.98
320.472.892.89
348.483.073.07
331.462.992.99
424.594.474.47
442.584.614.61
492.585.495.49
431.603.933.93
474.655.625.62
362.512.582.58
404.603.753.75
430.634.284.28
482.714.924.92
392.542.852.85
418.582.692.69
417.592.262.26
402.583.453.45
334.462.982.98
424.634.654.65
316.443.793.79
376.493.553.55
438.564.854.85