Basic Information
ID: ALA2405916
Type: Binding
Description: Inhibition of human 11beta-HSD1 expressed in HEK293 cell microsomes assessed as inhibition of [3H]cortisone conversion to [3H]cortisol at 1 uM by scintillation proximity assay
Organism: Homo sapiens
Cell type: HEK293
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2405916
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.69 | 6.41 | 6.41 |
| 288.48 | 4.95 | 4.95 |
| 302.46 | 5.04 | 5.04 |
| 517.46 | 5.61 | 5.61 |
| 481.63 | 4.91 | 4.91 |
| 447.57 | 3.46 | 3.46 |
| 460.60 | 4.69 | 4.69 |
| 304.43 | 4.05 | 4.05 |
| 318.46 | 4.01 | 4.01 |
| 320.45 | 4.99 | 4.99 |
| 336.47 | 3.06 | 3.06 |
| 350.46 | 2.19 | 2.19 |
| 332.44 | 3.19 | 3.19 |
| 290.47 | 5.93 | 5.93 |
| 299.46 | 5.04 | 5.04 |
| 399.60 | 5.99 | 5.99 |
| 410.58 | 6.67 | 6.67 |
| 450.71 | 6.98 | 6.98 |
| 320.47 | 2.89 | 2.89 |
| 348.48 | 3.07 | 3.07 |
| 331.46 | 2.99 | 2.99 |
| 424.59 | 4.47 | 4.47 |
| 442.58 | 4.61 | 4.61 |
| 492.58 | 5.49 | 5.49 |
| 431.60 | 3.93 | 3.93 |
| 474.65 | 5.62 | 5.62 |
| 362.51 | 2.58 | 2.58 |
| 404.60 | 3.75 | 3.75 |
| 430.63 | 4.28 | 4.28 |
| 482.71 | 4.92 | 4.92 |
| 392.54 | 2.85 | 2.85 |
| 418.58 | 2.69 | 2.69 |
| 417.59 | 2.26 | 2.26 |
| 402.58 | 3.45 | 3.45 |
| 334.46 | 2.98 | 2.98 |
| 424.63 | 4.65 | 4.65 |
| 316.44 | 3.79 | 3.79 |
| 376.49 | 3.55 | 3.55 |
| 438.56 | 4.85 | 4.85 |