Basic Information
ID: ALA2405920
Type: Binding
Description: Inhibition of mouse 11beta-HSD1 expressed in HEK293 cell microsomes assessed as inhibition of [3H]cortisone conversion to [3H]cortisol by scintillation proximity assay
Organism: Mus musculus
Cell type: HEK293
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2405920
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 470.69 | 6.41 | 6.41 |
| 336.47 | 3.21 | 3.21 |
| 288.48 | 4.95 | 4.95 |
| 302.46 | 5.04 | 5.04 |
| 318.46 | 4.01 | 4.01 |
| 410.58 | 6.67 | 6.67 |
| 450.71 | 6.98 | 6.98 |
| 424.59 | 4.47 | 4.47 |
| 442.58 | 4.61 | 4.61 |
| 474.65 | 5.62 | 5.62 |
| 430.63 | 4.28 | 4.28 |
| 482.71 | 4.92 | 4.92 |
| 322.49 | 3.12 | 3.12 |
| 424.63 | 4.65 | 4.65 |
| 376.49 | 3.55 | 3.55 |