Basic Information
ID: ALA2405976
Type: Binding
Description: Inhibition of p38 MAPK-mediated TNFalpha production in LPS-induced human PBMC preincubated for 5 mins prior to LPS-treatment measured after 6 hrs by ELISA
Format: BAO_0000019
Organism: Homo sapiens
Target: MAP kinase p38(ALA2094115)
Document: ALA2401637
Inhibition of p38 MAPK-mediated TNFalpha production in LPS-induced human PBMC preincubated for 5 mins prior to LPS-treatment measured after 6 hrs by ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2405976
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.43 | 4.05 | 4.05 |
| 410.93 | 5.52 | 5.52 |
| 410.93 | 5.52 | 5.52 |
| 410.93 | 5.52 | 5.52 |
| 394.47 | 5.01 | 5.01 |
| 444.48 | 5.89 | 5.89 |
| 376.48 | 4.87 | 4.87 |
| 392.48 | 4.57 | 4.57 |
| 391.50 | 4.45 | 4.45 |
| 406.51 | 4.88 | 4.88 |
| 401.49 | 4.74 | 4.74 |
| 406.51 | 4.36 | 4.36 |
| 433.58 | 4.93 | 4.93 |
| 447.56 | 4.57 | 4.57 |
| 489.60 | 4.34 | 4.34 |
| 487.63 | 5.49 | 5.49 |
| 377.47 | 4.26 | 4.26 |
| 377.47 | 4.26 | 4.26 |
| 377.47 | 4.26 | 4.26 |
| 395.46 | 4.40 | 4.40 |
| 462.58 | 4.10 | 4.10 |
| 391.50 | 4.57 | 4.57 |