Basic Information
ID: ALA2405978
Type: Binding
Description: Inhibition of human p38beta expressed in Escherichia coli using MBP as substrate preincubated for 10 mins prior to substrate addition measured after 45 mins by microbeta scintillation counting analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2405978
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 346.46 | 3.27 | 3.27 |
| 411.91 | 4.92 | 4.92 |
| 443.43 | 4.05 | 4.05 |
| 394.86 | 5.05 | 5.05 |
| 410.93 | 5.52 | 5.52 |
| 410.93 | 5.52 | 5.52 |
| 410.93 | 5.52 | 5.52 |
| 394.47 | 5.01 | 5.01 |
| 444.48 | 5.89 | 5.89 |
| 376.48 | 4.87 | 4.87 |
| 392.48 | 4.57 | 4.57 |
| 391.50 | 4.45 | 4.45 |
| 406.51 | 4.88 | 4.88 |
| 401.49 | 4.74 | 4.74 |
| 406.51 | 4.36 | 4.36 |
| 433.58 | 4.93 | 4.93 |
| 447.56 | 4.57 | 4.57 |
| 489.60 | 4.34 | 4.34 |
| 487.63 | 5.49 | 5.49 |
| 377.47 | 4.26 | 4.26 |
| 377.47 | 4.26 | 4.26 |
| 377.47 | 4.26 | 4.26 |
| 395.46 | 4.40 | 4.40 |
| 462.58 | 4.10 | 4.10 |
| 391.50 | 4.57 | 4.57 |
| 333.39 | 3.62 | 3.62 |
| 347.42 | 3.63 | 3.63 |
| 375.47 | 4.68 | 4.68 |
| 405.45 | 4.10 | 4.10 |