Basic Information
ID: ALA2406145
Type: Binding
Description: Inhibition of GST-tagged Plk1 (unknown origin) assessed as inhibition of DEKTDDED phosphorylation at Thr1342 after 60 mins by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2406145
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.45 | 3.44 | 3.44 |
| 415.46 | 2.56 | 2.56 |
| 502.39 | 4.52 | 4.52 |
| 462.45 | 4.37 | 4.37 |
| 406.47 | 3.58 | 3.58 |
| 394.45 | 3.44 | 3.44 |
| 402.50 | 3.83 | 3.83 |
| 383.48 | 2.96 | 2.96 |
| 376.46 | 3.30 | 3.30 |
| 430.43 | 3.84 | 3.84 |
| 448.42 | 3.98 | 3.98 |
| 456.47 | 4.22 | 4.22 |
| 442.45 | 3.83 | 3.83 |
| 408.44 | 2.43 | 2.43 |
| 404.47 | 2.68 | 2.68 |
| 404.47 | 2.68 | 2.68 |
| 422.46 | 2.82 | 2.82 |
| 410.48 | 4.22 | 4.22 |
| 446.46 | 4.50 | 4.50 |
| 453.48 | 4.23 | 4.23 |
| 412.46 | 3.01 | 3.01 |
| 418.44 | 3.08 | 3.08 |
| 418.44 | 3.08 | 3.08 |
| 432.46 | 3.10 | 3.10 |
| 432.46 | 3.10 | 3.10 |
| 432.46 | 3.10 | 3.10 |
| 425.52 | 2.73 | 2.73 |
| 411.49 | 2.34 | 2.34 |
| 407.46 | 2.61 | 2.61 |
| 421.49 | 2.62 | 2.62 |