Basic Information
ID: ALA2406231
Type: Binding
Description: Inhibition of human wild-type ABL (Ser229 to Gln513)-mediated phosphorylation of biotinylated poly-Glu-Tyr expressed in Escherichia coli BL21(DE3) preincubated for 30 to 60 mins prior to substrate addition by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2406231
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 398.48 | 3.33 | 3.33 |
| 493.62 | 4.59 | 4.59 |
| 392.44 | 2.54 | 2.54 |
| 562.68 | 7.16 | 7.16 |
| 532.57 | 4.46 | 4.46 |
| 567.57 | 6.32 | 6.32 |
| 522.57 | 6.41 | 6.41 |
| 507.60 | 5.67 | 5.67 |
| 492.59 | 6.08 | 6.08 |
| 729.85 | 9.44 | 9.44 |
| 563.67 | 6.43 | 6.43 |
| 620.76 | 6.36 | 6.36 |
| 661.81 | 5.66 | 5.66 |
| 648.77 | 5.74 | 5.74 |
| 522.57 | 6.41 | 6.41 |
| 492.59 | 6.08 | 6.08 |