Basic Information
ID: ALA2410096
Type: Binding
Description: Inhibition of recombinant HDAC8 (unknown origin) expressed in Escherichia coli BL21 using MAL as substrate incubated for 15 mins prior to substrate addition measured after 60 mins by fluorescence plate reader analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2410096
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.45 | 3.99 | 3.99 |
| 419.58 | 5.60 | 5.60 |
| 402.52 | 4.45 | 4.45 |
| 402.52 | 4.45 | 4.45 |
| 418.52 | 4.16 | 4.16 |
| 416.55 | 4.32 | 4.32 |
| 416.55 | 4.32 | 4.32 |
| 402.52 | 4.45 | 4.45 |
| 402.52 | 4.45 | 4.45 |
| 478.62 | 6.20 | 6.20 |
| 478.62 | 6.20 | 6.20 |
| 540.74 | ||
| 426.48 | 3.48 | 3.48 |
| 530.59 | 5.34 | 5.34 |
| 440.46 | 3.68 | 3.68 |
| 321.34 | 2.27 | 2.27 |
| 552.64 | 4.84 | 4.84 |
| 494.56 | 3.45 | 3.45 |
| 452.52 | 3.19 | 3.19 |
| 455.52 | 2.97 | 2.97 |
| 413.48 | 2.71 | 2.71 |
| 399.45 | 2.84 | 2.84 |
| 472.64 | 5.95 | 5.95 |
| 433.60 | 5.47 | 5.47 |
| 446.51 | 5.14 | 5.14 |
| 472.55 | 5.65 | 5.65 |
| 475.35 | 4.75 | 4.75 |
| 426.48 | 3.99 | 3.99 |
| 412.45 | 3.69 | 3.69 |