Basic Information
ID: ALA2410099
Type: Binding
Description: Inhibition of recombinant His-tagged HDAC6 (unknown origin) using Fluor-de-Lys SIRT1 as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins by fluorescence plate reader analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: Histone deacetylase 6(ALA1865)
Document: ALA2407081
Inhibition of recombinant His-tagged HDAC6 (unknown origin) using Fluor-de-Lys SIRT1 as substrate incubated for 3 hrs prior to substrate addition measured after 60 mins by fluorescence plate reader analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2410099
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.45 | 3.99 | 3.99 |
| 419.58 | 5.60 | 5.60 |
| 402.52 | 4.45 | 4.45 |
| 402.52 | 4.45 | 4.45 |
| 418.52 | 4.16 | 4.16 |
| 416.55 | 4.32 | 4.32 |
| 416.55 | 4.32 | 4.32 |
| 402.52 | 4.45 | 4.45 |
| 402.52 | 4.45 | 4.45 |
| 478.62 | 6.20 | 6.20 |
| 478.62 | 6.20 | 6.20 |
| 540.74 | ||
| 426.48 | 3.48 | 3.48 |
| 530.59 | 5.34 | 5.34 |
| 440.46 | 3.68 | 3.68 |
| 321.34 | 2.27 | 2.27 |
| 552.64 | 4.84 | 4.84 |
| 494.56 | 3.45 | 3.45 |
| 452.52 | 3.19 | 3.19 |
| 455.52 | 2.97 | 2.97 |
| 413.48 | 2.71 | 2.71 |
| 399.45 | 2.84 | 2.84 |
| 472.64 | 5.95 | 5.95 |
| 433.60 | 5.47 | 5.47 |
| 446.51 | 5.14 | 5.14 |
| 472.55 | 5.65 | 5.65 |
| 475.35 | 4.75 | 4.75 |
| 426.48 | 3.99 | 3.99 |
| 412.45 | 3.69 | 3.69 |