Basic Information
ID: ALA2410318
Type: Binding
Description: Inhibition of N-terminal GST-tagged human PLK4 (1 to 391 amino acids) expressed in Escherichia coli using TMB as substrate after 30 mins by indirect ELISA assay
Format: BAO_0000019
Organism: Homo sapiens
Target: Serine/threonine-protein kinase PLK4(ALA3788)
Document: ALA2406977
Inhibition of N-terminal GST-tagged human PLK4 (1 to 391 amino acids) expressed in Escherichia coli using TMB as substrate after 30 mins by indirect ELISA assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2410318
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 520.95 | 5.01 | 5.01 |
| 237.26 | 2.88 | 2.88 |
| 386.48 | 4.64 | 4.64 |
| 407.43 | 4.92 | 4.92 |
| 364.41 | 4.62 | 4.62 |
| 364.41 | 4.62 | 4.62 |
| 392.46 | 5.18 | 5.18 |
| 394.43 | 4.63 | 4.63 |
| 364.41 | 4.62 | 4.62 |
| 398.85 | 5.27 | 5.27 |
| 378.44 | 4.93 | 4.93 |
| 394.43 | 4.63 | 4.63 |
| 380.41 | 4.33 | 4.33 |
| 363.42 | 5.23 | 5.23 |
| 420.52 | 5.29 | 5.29 |
| 450.54 | 5.30 | 5.30 |
| 462.56 | 4.37 | 4.37 |
| 492.58 | 4.38 | 4.38 |
| 380.62 | 4.31 | 4.31 |
| 394.65 | 4.33 | 4.33 |
| 439.10 | 4.72 | 4.72 |
| 237.26 | 2.88 | 2.88 |
| 237.26 | 2.88 | 2.88 |
| 332.15 | 3.35 | 3.35 |
| 262.27 | 2.45 | 2.45 |
| 261.28 | 3.06 | 3.06 |
| 261.28 | 3.06 | 3.06 |
| 279.27 | 3.19 | 3.19 |
| 279.27 | 3.19 | 3.19 |
| 295.73 | 3.71 | 3.71 |
| 295.73 | 3.71 | 3.71 |
| 291.31 | 3.06 | 3.06 |
| 318.34 | 2.42 | 2.42 |
| 318.34 | 3.01 | 3.01 |
| 318.34 | 3.01 | 3.01 |