Basic Information
ID: ALA2410848
Type: Binding
Description: Antagonist activity at human alpha4beta2 nAChR expressed in HEK-tsA201 cells assessed as inhibition of epibatidine-induced intracellular calcium level by fluorescence plate reader analysis
Organism: Homo sapiens
Cell type: HEK-tsA201
Activity Charts
Bioactivity
Activity Types for Assay ALA2410848
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 167.30 | 2.42 | 2.42 |
| 270.33 | 3.35 | 3.35 |
| 645.20 | 6.70 | 6.70 |
| 268.32 | 3.21 | 3.21 |
| 270.33 | 3.43 | 3.43 |
| 282.34 | 3.60 | 3.60 |
| 266.30 | 2.65 | 2.65 |
| 254.29 | 2.90 | 2.90 |
| 333.18 | 3.66 | 3.66 |
| 288.73 | 3.55 | 3.55 |
| 282.34 | 3.46 | 3.46 |
| 311.39 | 3.72 | 3.72 |
| 325.41 | 4.11 | 4.11 |
| 335.20 | 3.89 | 3.89 |
| 290.75 | 3.78 | 3.78 |
| 257.29 | 2.52 | 2.52 |
| 284.36 | 3.69 | 3.69 |
| 313.40 | 3.94 | 3.94 |
| 327.43 | 4.33 | 4.33 |
| 341.46 | 4.72 | 4.72 |
| 355.48 | 5.11 | 5.11 |
| 347.42 | 4.87 | 4.87 |
| 365.41 | 5.01 | 5.01 |
| 365.41 | 5.01 | 5.01 |
| 365.41 | 5.01 | 5.01 |
| 381.86 | 5.52 | 5.52 |
| 377.44 | 4.87 | 4.87 |
| 361.45 | 4.73 | 4.73 |
| 339.44 | 4.11 | 4.11 |