Assay Report Card

Basic Information

ID: ALA2411080

Type: Binding

Description: Antagonist activity at P2X7 in Sprague-Dawley rat synaptosome assessed as inhibition of BzATP-induced [3H]D-aspartate efflux preincubated at 50 uM for 8 mins by liquid scintillation counting in absence of extracellular Ca2+

Organism: Rattus norvegicus

Tissue: Brain

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
338.452.892.89