ID: ALA2411713
Type: Binding
Description: Inhibition of NOX2 in human THP1 cells assessed as suppression of TPA-induced membrane translocation of p47phox at 20 uM incubated for 1 hr prior to TPA challenge measured after 12 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: Cytochrome b-245 heavy chain(ALA1287627)
Document: ALA2407018
Inhibition of NOX2 in human THP1 cells assessed as suppression of TPA-induced membrane translocation of p47phox at 20 uM incubated for 1 hr prior to TPA challenge measured after 12 hrs by Western blot analysis: 1
Bioactivity
Activity Types for Assay ALA2411713
Inhibition
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
286.24 | 2.28 | 2.28 |
302.24 | 1.99 | 1.99 |