Basic Information
ID: ALA2411715
Type: Binding
Description: Inhibition of NOX2 in human THP1 cells assessed as suppression of TPA-induced intracellular ROS accumulation at 20 uM incubated for 1 hr prior to TPA challenge measured after 24 hrs by flow cytometric analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: Cytochrome b-245 heavy chain(ALA1287627)
Document: ALA2407018
Inhibition of NOX2 in human THP1 cells assessed as suppression of TPA-induced intracellular ROS accumulation at 20 uM incubated for 1 hr prior to TPA challenge measured after 24 hrs by flow cytometric analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2411715
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 286.24 | 2.28 | 2.28 |