Basic Information
ID: ALA2411719
Type: Binding
Description: Inhibition of NOX2 in human THP1 cells assessed as downregulation of TPA-induced CD14 mRNA expression at 0.2 to 2 uM incubated for 1 hr prior to TPA challenge measured after 24 hrs by RT-PCR analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: Cytochrome b-245 heavy chain(ALA1287627)
Document: ALA2407018
Inhibition of NOX2 in human THP1 cells assessed as downregulation of TPA-induced CD14 mRNA expression at 0.2 to 2 uM incubated for 1 hr prior to TPA challenge measured after 24 hrs by RT-PCR analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2411719
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 286.24 | 2.28 | 2.28 |