Assay Report Card

Basic Information

ID: ALA2411721

Type: Binding

Description: Inhibition of NOX2 in human THP1 cells assessed as downregulation of TPA-induced CD36 mRNA expression at 20 uM incubated for 1 hr prior to TPA challenge measured after 24 hrs by RT-PCR analysis

Organism: Homo sapiens

Cell type: THP-1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
270.242.582.58
254.242.872.87
286.242.282.28
302.241.991.99