Basic Information
ID: ALA2411722
Type: Binding
Description: Inhibition of NOX2 in human THP1 cells assessed as downregulation of TPA-induced CD14 mRNA expression at 20 uM incubated for 1 hr prior to TPA challenge measured after 24 hrs by RT-PCR analysis
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA2411722
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 270.24 | 2.58 | 2.58 |
| 254.24 | 2.87 | 2.87 |
| 286.24 | 2.28 | 2.28 |
| 302.24 | 1.99 | 1.99 |