Basic Information
ID: ALA2411903
Type: Binding
Description: Inhibition of chymotryptic-like activity of human 20S proteasome using Suc-LLVY-AMC as substrate measured every min over 30 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2411903
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.25 | ||
| 432.52 | 5.67 | 5.67 |
| 388.51 | 6.43 | 6.43 |
| 388.51 | 6.43 | 6.43 |
| 386.50 | 6.93 | 6.93 |
| 446.55 | 5.76 | 5.76 |
| 460.58 | 6.15 | 6.15 |
| 522.65 | 7.33 | 7.33 |
| 431.54 | 5.07 | 5.07 |
| 461.57 | 5.54 | 5.54 |
| 505.57 | 6.06 | 6.06 |
| 475.59 | 5.73 | 5.73 |
| 495.02 | 6.80 | 6.80 |
| 528.57 | 7.17 | 7.17 |
| 450.54 | 5.74 | 5.74 |
| 490.60 | 6.16 | 6.16 |
| 478.57 | 6.29 | 6.29 |
| 495.02 | 6.80 | 6.80 |
| 539.47 | 6.91 | 6.91 |
| 450.54 | 5.74 | 5.74 |
| 370.45 | 4.24 | 4.24 |
| 412.49 | 4.50 | 4.50 |
| 474.56 | 5.79 | 5.79 |
| 524.64 | 5.65 | 5.65 |
| 547.66 | 6.12 | 6.12 |
| 609.73 | 7.41 | 7.41 |
| 547.66 | 5.46 | 5.46 |
| 645.78 | 6.96 | 6.96 |
| 705.83 | 6.98 | 6.98 |
| 659.81 | 7.10 | 7.10 |
| 609.75 | 6.06 | 6.06 |
| 612.75 | 5.38 | 5.38 |
| 595.74 | 7.77 | 7.77 |
| 611.74 | 7.48 | 7.48 |
| 685.82 | 7.80 | 7.80 |
| 601.79 | 8.15 | 8.15 |
| 615.76 | 6.95 | 6.95 |
| 506.67 | 6.87 | 6.87 |
| 538.67 | 5.55 | 5.55 |
| 565.72 | 7.76 | 7.76 |
| 539.47 | 6.91 | 6.91 |
| 490.60 | 6.16 | 6.16 |
| 515.61 | 6.03 | 6.03 |
| 533.63 | 5.26 | 5.26 |
| 505.62 | 5.74 | 5.74 |
| 236.32 | 2.95 | 2.95 |
| 476.58 | 5.12 | 5.12 |