Basic Information
ID: ALA2412567
Type: Binding
Description: Antagonist activity at human alpha6/alpha3beta2beta3 nAChR expressed in human SHEP1 cells assessed as inhibition of carbamylcholine-induced 86Rb+ ion efflux preincubated for 10 mins by liquid scintillation counting analysis relative to control
Organism: Homo sapiens
Cell type: SHEP1
Activity Charts
Bioactivity
Activity Types for Assay ALA2412567
Efficacy
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 162.24 | 1.85 | 1.85 |
| 262.35 | 1.96 | 1.96 |
| 390.40 | 2.35 | 2.35 |
| 404.43 | 2.69 | 2.69 |
| 390.40 | 2.21 | 2.21 |