Basic Information
ID: ALA2412580
Type: Binding
Description: Inhibition of TNFalpha-induced NF-kappaB activation (unknown origin) expressed in human HeLa cells pretreated 30 mins before TNFalpha addition after 7 hrs by luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Unchecked(ALA612545)
Document: ALA2406967
Inhibition of TNFalpha-induced NF-kappaB activation (unknown origin) expressed in human HeLa cells pretreated 30 mins before TNFalpha addition after 7 hrs by luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2412580
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 526.54 | 0.77 | 0.77 |
| 510.54 | 1.56 | 1.56 |
| 470.61 | 3.54 | 3.54 |
| 526.54 | 0.43 | 0.43 |
| 528.55 | 0.51 | 0.51 |
| 486.61 | 2.75 | 2.75 |
| 526.54 | 0.77 | 0.77 |
| 452.59 | 4.35 | 4.35 |
| 454.61 | 4.43 | 4.43 |
| 510.54 | 1.46 | 1.46 |
| 526.54 | 0.53 | 0.53 |
| 542.54 | -0.12 | -0.12 |
| 542.54 | -0.12 | -0.12 |
| 528.55 | 0.65 | 0.65 |
| 488.62 | 2.45 | 2.45 |
| 488.62 | 2.45 | 2.45 |
| 292.29 | -0.37 | -0.37 |
| 324.29 | -1.07 | -1.07 |
| 366.32 | -0.50 | -0.50 |
| 414.41 | 1.15 | 1.15 |
| 414.41 | 1.05 | 1.05 |