Assay Report Card

Basic Information

ID: ALA2412621

Type: Binding

Description: Inhibition of Hedgehog signaling in mouse C3H10T1/2 cells assessed as downregulation of Gli1 mRNA expression at 5 uM after 24 hrs by RT-PCR analysis relative to 20(S)-hydroxycholesterol and 22(S)-hydroxycholesterol

Organism: Mus musculus

Cell type: C3H 10T1/2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
138.121.091.09
384.657.627.62
266.475.035.03
476.708.478.47
370.586.896.89
405.027.547.54
400.606.906.90
412.617.097.09
386.586.606.60
414.596.596.59
385.596.476.47
399.626.936.93