Basic Information
ID: ALA2412855
Type: Binding
Description: Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylation
Organism: Homo sapiens
Cell type: HCT-116
Activity Charts
Bioactivity
Activity Types for Assay ALA2412855
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 485.47 | 5.02 | 5.02 |
| 426.48 | 4.00 | 4.00 |
| 472.55 | 3.83 | 3.83 |
| 431.50 | 3.62 | 3.62 |
| 440.51 | 4.19 | 4.19 |
| 458.55 | 4.73 | 4.73 |
| 458.55 | 4.73 | 4.73 |
| 459.54 | 4.13 | 4.13 |
| 458.55 | 4.73 | 4.73 |
| 455.52 | 4.01 | 4.01 |
| 451.53 | 5.28 | 5.28 |
| 457.56 | 5.34 | 5.34 |
| 442.48 | 3.17 | 3.17 |
| 426.48 | 4.00 | 4.00 |
| 469.47 | 5.14 | 5.14 |
| 443.51 | 4.33 | 4.33 |
| 444.50 | 3.22 | 3.22 |
| 430.51 | 3.58 | 3.58 |
| 431.50 | 3.62 | 3.62 |
| 447.56 | 4.85 | 4.85 |
| 479.56 | 3.53 | 3.53 |
| 416.49 | 3.71 | 3.71 |
| 494.58 | 3.50 | 3.50 |
| 417.47 | 3.83 | 3.83 |
| 447.56 | 4.85 | 4.85 |
| 458.52 | 4.08 | 4.08 |
| 426.48 | 4.00 | 4.00 |
| 469.47 | 5.14 | 5.14 |
| 443.51 | 4.33 | 4.33 |
| 444.50 | 3.22 | 3.22 |
| 431.50 | 3.62 | 3.62 |
| 445.52 | 4.27 | 4.27 |
| 440.51 | 4.19 | 4.19 |
| 447.56 | 4.85 | 4.85 |
| 479.56 | 3.53 | 3.53 |
| 480.55 | 2.77 | 2.77 |
| 508.60 | 3.37 | 3.37 |
| 446.47 | 4.03 | 4.03 |
| 416.49 | 3.71 | 3.71 |
| 444.54 | 4.19 | 4.19 |
| 458.52 | 4.08 | 4.08 |
| 417.47 | 3.83 | 3.83 |
| 431.50 | 4.13 | 4.13 |
| 475.55 | 4.15 | 4.15 |
| 485.47 | 5.02 | 5.02 |
| 401.47 | 4.12 | 4.12 |
| 391.44 | 2.85 | 2.85 |