Basic Information
ID: ALA2415509
Type: Binding
Description: Inhibition of DGAT-1-mediated triglyceride synthesis in human HT-29 cells using [3H]-glycerol as substrate incubated for 1 hr prior to substrate addition measured after 5 hrs by scintillation counting analysis
Organism: Homo sapiens
Cell type: HT-29
Activity Charts
Bioactivity
Activity Types for Assay ALA2415509
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.45 | 2.85 | 2.85 |
| 481.60 | 2.90 | 2.90 |
| 449.56 | 3.38 | 3.38 |
| 465.55 | 2.36 | 2.36 |
| 465.55 | 2.62 | 2.62 |
| 492.58 | 2.06 | 2.06 |
| 493.61 | 3.40 | 3.40 |
| 451.53 | 1.97 | 1.97 |
| 381.44 | 1.82 | 1.82 |
| 409.49 | 2.46 | 2.46 |
| 425.49 | 1.84 | 1.84 |
| 449.56 | 3.38 | 3.38 |
| 451.53 | 2.23 | 2.23 |
| 465.55 | 2.36 | 2.36 |
| 435.44 | 1.50 | 1.50 |
| 443.51 | 3.12 | 3.12 |
| 434.46 | 2.11 | 2.11 |
| 434.46 | 2.11 | 2.11 |
| 377.45 | 3.29 | 3.29 |
| 410.52 | 3.53 | 3.53 |
| 409.53 | 3.50 | 3.50 |
| 434.50 | 3.31 | 3.31 |
| 433.52 | 3.04 | 3.04 |
| 448.53 | 3.70 | 3.70 |
| 368.48 | 3.11 | 3.11 |
| 410.47 | 3.15 | 3.15 |
| 395.46 | 3.45 | 3.45 |
| 424.50 | 3.63 | 3.63 |
| 410.47 | 3.24 | 3.24 |
| 270.29 | 1.41 | 1.41 |
| 312.37 | 2.40 | 2.40 |
| 410.47 | 3.24 | 3.24 |
| 467.53 | 2.30 | 2.30 |
| 420.48 | 2.13 | 2.13 |
| 395.46 | 2.25 | 2.25 |
| 463.58 | 3.82 | 3.82 |