Basic Information
ID: ALA2415510
Type: Binding
Description: Inhibition of human full length DGAT-1 expressed in insect sf9 cells using [14C]decanoylCoA as substrate after 1.5 hrs by scintillation spectrometry
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA2415510
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.45 | 2.85 | 2.85 |
| 481.60 | 2.90 | 2.90 |
| 449.56 | 3.38 | 3.38 |
| 465.55 | 2.36 | 2.36 |
| 465.55 | 2.62 | 2.62 |
| 492.58 | 2.06 | 2.06 |
| 493.61 | 3.40 | 3.40 |
| 451.53 | 1.97 | 1.97 |
| 381.44 | 1.82 | 1.82 |
| 409.49 | 2.46 | 2.46 |
| 425.49 | 1.84 | 1.84 |
| 449.56 | 3.38 | 3.38 |
| 451.53 | 2.23 | 2.23 |
| 465.55 | 2.36 | 2.36 |
| 435.44 | 1.50 | 1.50 |
| 443.51 | 3.12 | 3.12 |
| 434.46 | 2.11 | 2.11 |
| 434.46 | 2.11 | 2.11 |
| 377.45 | 3.29 | 3.29 |
| 410.52 | 3.53 | 3.53 |
| 409.53 | 3.50 | 3.50 |
| 434.50 | 3.31 | 3.31 |
| 434.50 | 3.31 | 3.31 |
| 450.57 | 3.77 | 3.77 |
| 433.52 | 3.04 | 3.04 |
| 447.54 | 3.05 | 3.05 |
| 448.53 | 3.70 | 3.70 |
| 368.48 | 3.11 | 3.11 |
| 396.45 | 2.73 | 2.73 |
| 410.47 | 3.15 | 3.15 |
| 397.43 | 2.97 | 2.97 |
| 411.46 | 3.27 | 3.27 |
| 410.47 | 3.31 | 3.31 |
| 424.50 | 3.33 | 3.33 |
| 395.46 | 3.45 | 3.45 |
| 395.46 | 3.45 | 3.45 |
| 424.50 | 3.63 | 3.63 |
| 410.47 | 3.24 | 3.24 |
| 410.47 | 3.24 | 3.24 |
| 270.29 | 1.41 | 1.41 |
| 312.37 | 2.40 | 2.40 |
| 248.29 | 0.84 | 0.84 |
| 318.42 | 2.50 | 2.50 |
| 410.47 | 3.24 | 3.24 |
| 467.53 | 2.30 | 2.30 |
| 420.48 | 2.13 | 2.13 |
| 410.47 | 2.93 | 2.93 |
| 395.46 | 2.25 | 2.25 |
| 423.52 | 2.90 | 2.90 |
| 463.58 | 3.82 | 3.82 |