Basic Information
ID: ALA2415689
Type: Binding
Description: Inhibition of HDAC1/HDAC3/HDAC5/HDAC8 in human HeLa nuclear extract using Boc-Lys(acetyl)-AMC as substrate incubated for 5 mins prior to substrate measured after 30 mins by spectrophotometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2415689
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 308.38 | 0.53 | 0.53 |
| 321.37 | 2.25 | 2.25 |
| 397.47 | 3.83 | 3.83 |
| 221.26 | 0.69 | 0.69 |
| 297.35 | 2.26 | 2.26 |
| 434.53 | 2.79 | 2.79 |
| 468.55 | 2.98 | 2.98 |
| 454.52 | 3.11 | 3.11 |
| 334.42 | 1.22 | 1.22 |
| 368.43 | 1.42 | 1.42 |
| 354.41 | 1.55 | 1.55 |
| 320.39 | 1.13 | 1.13 |
| 354.41 | 1.33 | 1.33 |
| 340.38 | 1.46 | 1.46 |