Basic Information
ID: ALA2416034
Type: Binding
Description: Inhibition of ovine COX1 using arachidonic acid as substrate assessed as production of PGF2alpha preincubated for 10 mins followed by substrate addition measured after 2 mins by EIA in presence of stannous chloride
Organism: Ovis aries
Activity Charts
Bioactivity
Activity Types for Assay ALA2416034
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 381.38 | 3.51 | 3.51 |
| 337.33 | 3.79 | 3.79 |
| 392.18 | 5.19 | 5.19 |
| 343.31 | 4.44 | 4.44 |
| 363.34 | 5.58 | 5.58 |
| 319.31 | 4.49 | 4.49 |
| 303.24 | 4.02 | 4.02 |
| 347.37 | 4.19 | 4.19 |
| 361.39 | 4.50 | 4.50 |
| 365.36 | 4.33 | 4.33 |
| 381.81 | 4.85 | 4.85 |
| 426.26 | 4.95 | 4.95 |
| 377.39 | 4.20 | 4.20 |
| 353.39 | 4.25 | 4.25 |
| 313.28 | 4.43 | 4.43 |
| 327.31 | 4.74 | 4.74 |
| 331.27 | 4.57 | 4.57 |
| 347.73 | 5.08 | 5.08 |