Basic Information
ID: ALA2417225
Type: Functional
Description: Antiplasmodial activity against erythrocytic stages of chloroquine-resistant Plasmodium falciparum FcB1/Columbia incubated for 24 hrs followed by [3H]-hypoxanthine addition measured after 24 hrs by liquid scintillation spectrometry
Organism: Plasmodium falciparum
Strain: FcB1/Columbia
Activity Charts
Bioactivity
Activity Types for Assay ALA2417225
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.88 | 4.81 | 4.81 |
| 328.37 | 5.34 | 5.34 |
| 373.36 | 5.25 | 5.25 |
| 404.42 | 5.06 | 5.06 |
| 262.31 | 4.54 | 4.54 |
| 298.34 | 5.33 | 5.33 |
| 343.34 | 5.24 | 5.24 |
| 344.37 | 5.05 | 5.05 |
| 374.39 | 5.05 | 5.05 |
| 394.43 | 6.20 | 6.20 |
| 438.48 | 6.60 | 6.60 |
| 308.33 | 4.26 | 4.26 |
| 328.37 | 5.40 | 5.40 |
| 372.42 | 5.80 | 5.80 |
| 358.39 | 5.35 | 5.35 |
| 388.42 | 5.36 | 5.36 |
| 408.45 | 6.50 | 6.50 |
| 392.84 | 6.00 | 6.00 |
| 488.54 | 6.31 | 6.31 |
| 448.47 | 5.37 | 5.37 |
| 344.37 | 5.33 | 5.33 |
| 374.39 | 5.34 | 5.34 |
| 420.42 | 5.05 | 5.05 |
| 394.43 | 6.48 | 6.48 |
| 438.48 | 6.88 | 6.88 |
| 378.81 | 5.98 | 5.98 |
| 389.36 | 5.24 | 5.24 |
| 278.31 | 4.53 | 4.53 |
| 308.33 | 4.54 | 4.54 |
| 328.37 | 5.68 | 5.68 |
| 372.42 | 6.08 | 6.08 |
| 312.75 | 5.18 | 5.18 |
| 323.30 | 4.44 | 4.44 |
| 314.34 | 5.32 | 5.32 |
| 344.37 | 5.33 | 5.33 |
| 364.40 | 6.47 | 6.47 |
| 408.45 | 6.87 | 6.87 |
| 348.79 | 5.97 | 5.97 |
| 359.34 | 5.23 | 5.23 |
| 342.39 | 5.94 | 5.94 |