Basic Information
ID: ALA2421151
Type: Functional
Description: Negative allosteric modulation of human mGlu1 receptor expressed in HEK293A TREx cells assessed as calcium flux after 45 mins
Organism: Homo sapiens
Cell type: HEK293-A
Activity Charts
Bioactivity
Activity Types for Assay ALA2421151
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.49 | 3.21 | 3.21 |
| 376.50 | 3.06 | 3.06 |
| 376.50 | 3.06 | 3.06 |
| 326.44 | 2.16 | 2.16 |
| 328.46 | 2.84 | 2.84 |
| 340.47 | 2.84 | 2.84 |
| 354.50 | 3.23 | 3.23 |
| 368.53 | 3.62 | 3.62 |
| 326.44 | 2.30 | 2.30 |
| 340.47 | 2.69 | 2.69 |
| 351.49 | 3.19 | 3.19 |
| 273.38 | 2.02 | 2.02 |
| 299.42 | 2.56 | 2.56 |
| 313.45 | 2.95 | 2.95 |
| 327.47 | 3.34 | 3.34 |
| 313.45 | 2.80 | 2.80 |
| 313.45 | 2.95 | 2.95 |
| 355.53 | 3.83 | 3.83 |
| 287.41 | 2.41 | 2.41 |
| 313.45 | 2.95 | 2.95 |
| 365.52 | 3.58 | 3.58 |
| 319.41 | 1.34 | 1.34 |
| 357.52 | 3.25 | 3.25 |
| 352.48 | 2.59 | 2.59 |
| 352.48 | 2.59 | 2.59 |
| 352.48 | 2.59 | 2.59 |
| 369.48 | 3.33 | 3.33 |
| 369.48 | 3.33 | 3.33 |
| 369.48 | 3.33 | 3.33 |
| 375.52 | 3.67 | 3.67 |
| 376.50 | 3.06 | 3.06 |
| 376.50 | 3.06 | 3.06 |