Basic Information
ID: ALA2422303
Type: Binding
Description: Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assay
Organism: Homo sapiens
Cell type: HEK293-MSRII
Activity Charts
Bioactivity
Activity Types for Assay ALA2422303
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.46 | 4.09 | 4.09 |
| 393.51 | 4.92 | 4.92 |
| 383.56 | 5.63 | 5.63 |
| 329.47 | 4.46 | 4.46 |
| 359.45 | 3.88 | 3.88 |
| 391.47 | 4.32 | 4.32 |
| 411.89 | 4.67 | 4.67 |
| 381.90 | 5.25 | 5.25 |
| 381.90 | 5.25 | 5.25 |
| 381.90 | 5.25 | 5.25 |
| 379.44 | 3.81 | 3.81 |
| 393.47 | 4.37 | 4.37 |
| 407.50 | 4.68 | 4.68 |
| 408.48 | 4.08 | 4.08 |
| 402.88 | 4.58 | 4.58 |
| 315.44 | 4.07 | 4.07 |
| 335.86 | 4.41 | 4.41 |
| 331.44 | 3.77 | 3.77 |
| 335.86 | 4.41 | 4.41 |
| 353.85 | 4.55 | 4.55 |
| 345.42 | 3.49 | 3.49 |
| 315.44 | 4.21 | 4.21 |
| 377.51 | 5.56 | 5.56 |
| 377.51 | 5.21 | 5.21 |