Basic Information
ID: ALA2422341
Type: Binding
Description: Antagonist activity at alpha-1B adrenoreceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced tissue contraction after 30 mins by Schild plot analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Spleen
Activity Charts
Bioactivity
Activity Types for Assay ALA2422341
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 458.43 | 2.53 | 2.53 |
| 354.41 | 2.98 | 2.98 |
| 391.85 | 3.25 | 3.25 |
| 393.87 | 2.44 | 2.44 |
| 429.34 | 2.47 | 2.47 |