Assay Report Card

Basic Information

ID: ALA2422719

Type: Binding

Description: Agonist activity at LXRbeta in mouse BV2 cells assessed as degradation of intracellular soluble amyloid beta42 at 1 uM preincubated for 18 hrs followed by soluble amyloid beta42 addition measured after 24 hrs by ELISA relative to vehicle-treated control

Organism: Mus musculus

Cell type: BV-2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
582.068.098.09
295.364.094.09
278.313.353.35
289.334.024.02
283.282.602.60
277.283.653.65
282.252.862.86
243.262.772.77
259.333.243.24
283.333.273.27
269.302.882.88
313.353.283.28
288.304.324.32