Basic Information
ID: ALA2422748
Type: Binding
Description: Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition measured after 20 mins by liquid scintillation counting analysis in presence of NaH[14C]O3
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2422748
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.58 | 3.21 | 3.21 |
| 474.49 | 3.49 | 3.49 |
| 440.94 | 3.13 | 3.13 |
| 439.95 | 3.73 | 3.73 |
| 439.95 | 3.73 | 3.73 |
| 440.94 | 3.13 | 3.13 |
| 447.54 | 3.16 | 3.16 |
| 447.54 | 3.16 | 3.16 |
| 447.54 | 3.16 | 3.16 |
| 446.56 | 3.19 | 3.19 |
| 446.56 | 3.19 | 3.19 |
| 474.61 | 3.97 | 3.97 |
| 407.47 | 3.15 | 3.15 |
| 375.43 | 3.51 | 3.51 |
| 406.49 | 2.48 | 2.48 |
| 434.54 | 3.09 | 3.09 |
| 420.52 | 2.92 | 2.92 |
| 432.53 | 3.06 | 3.06 |
| 448.57 | 3.48 | 3.48 |
| 434.54 | 3.09 | 3.09 |
| 420.52 | 2.92 | 2.92 |
| 448.57 | 3.43 | 3.43 |