Basic Information
ID: ALA2423005
Type: Binding
Description: Inhibition of human recombinant GST-tagged SIRT2 using KI179 as substrate at 50 uM preincubated for 5 mins followed by enzyme addition measured after 1 hr by fluorescence assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2423005
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.54 | 4.03 | 4.03 |
| 455.58 | 3.39 | 3.39 |
| 441.60 | 3.75 | 3.75 |
| 427.57 | 3.71 | 3.71 |
| 485.61 | 3.40 | 3.40 |
| 457.60 | 3.24 | 3.24 |
| 480.63 | 4.23 | 4.23 |
| 510.66 | 4.24 | 4.24 |
| 586.76 | 5.81 | 5.81 |
| 414.53 | 3.42 | 3.42 |
| 394.50 | 0.99 | 0.99 |
| 408.52 | 1.38 | 1.38 |
| 540.69 | 2.67 | 2.67 |
| 408.57 | 2.74 | 2.74 |
| 453.61 | 3.21 | 3.21 |
| 467.64 | 3.60 | 3.60 |
| 495.69 | 4.38 | 4.38 |
| 454.60 | 2.61 | 2.61 |
| 568.70 | 2.35 | 2.35 |
| 518.68 | 2.98 | 2.98 |
| 421.56 | 2.99 | 2.99 |
| 467.68 | 4.70 | 4.70 |
| 481.71 | 5.09 | 5.09 |
| 412.56 | 3.24 | 3.24 |
| 430.55 | 3.38 | 3.38 |
| 505.69 | 2.73 | 2.73 |
| 565.70 | 1.19 | 1.19 |
| 412.56 | 3.24 | 3.24 |
| 364.51 | 1.78 | 1.78 |
| 476.64 | 3.62 | 3.62 |
| 412.99 | 1.97 | 1.97 |
| 526.66 | 2.99 | 2.99 |