Assay Report Card

Basic Information

ID: ALA2423071

Type: Binding

Description: Binding affinity to human GFP-tagged NPC1L1 L1072T/L1168I mutant expressed in HEK293 cells assessed as localization to endoplasmic reticulum and plasma membrane at 10 uM after 24 hrs by fluorescence microscopic analysis

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
288.433.883.88
409.434.894.89
386.667.397.39
402.666.366.36
402.666.506.50
402.666.366.36
402.666.366.36
556.888.488.48