Basic Information
ID: ALA2423076
Type: Binding
Description: Binding affinity to human GFP-tagged NPC1L1 L1072T/L1168I mutant expressed in HEK293 cells assessed as localization to endoplasmic reticulum and plasma membrane after 24 hrs by fluorescence microscopic analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2423076
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 374.57 | 5.43 | 5.43 |
| 387.61 | 5.09 | 5.09 |
| 401.64 | 5.43 | 5.43 |
| 402.66 | 6.50 | 6.50 |
| 402.66 | 6.36 | 6.36 |
| 404.68 | 6.44 | 6.44 |
| 404.68 | 6.44 | 6.44 |
| 400.65 | 6.57 | 6.57 |
| 485.80 | 7.77 | 7.77 |
| 444.66 | 5.53 | 5.53 |
| 472.71 | 6.14 | 6.14 |
| 500.77 | 6.92 | 6.92 |
| 528.82 | 7.70 | 7.70 |
| 514.75 | 5.91 | 5.91 |
| 527.79 | 5.82 | 5.82 |
| 532.77 | 4.86 | 4.86 |
| 551.81 | 4.99 | 4.99 |
| 535.81 | 5.87 | 5.87 |
| 535.81 | 5.87 | 5.87 |
| 533.79 | 6.08 | 6.08 |
| 533.79 | 5.79 | 5.79 |
| 531.78 | 6.00 | 6.00 |
| 517.80 | 6.82 | 6.82 |
| 402.66 | 6.65 | 6.65 |
| 388.64 | 6.11 | 6.11 |
| 360.58 | 5.33 | 5.33 |
| 373.58 | 4.83 | 4.83 |