Basic Information
ID: ALA2423205
Type: Binding
Description: Inhibition of human BCRP expressed in MDCK2 cells assessed as accumulation of pheophorbide-A preincubated for 30 mins before pheophorbide-A addition measured after 120 mins by flow cytometry
Organism: Homo sapiens
Cell type: MDCK-II
Activity Charts
Bioactivity
Activity Types for Assay ALA2423205
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 372.37 | 3.50 | 3.50 |
| 272.30 | 4.61 | 4.61 |
| 272.30 | 4.61 | 4.61 |
| 372.37 | 3.50 | 3.50 |
| 358.35 | 3.20 | 3.20 |
| 328.32 | 3.19 | 3.19 |
| 252.27 | 3.47 | 3.47 |
| 469.58 | 3.64 | 3.64 |
| 342.35 | 3.49 | 3.49 |
| 358.35 | 3.20 | 3.20 |
| 328.32 | 3.19 | 3.19 |
| 302.33 | 4.62 | 4.62 |
| 332.36 | 4.63 | 4.63 |
| 320.32 | 4.76 | 4.76 |
| 288.30 | 4.32 | 4.32 |
| 318.33 | 4.33 | 4.33 |
| 348.35 | 4.34 | 4.34 |
| 336.32 | 4.47 | 4.47 |
| 302.33 | 4.62 | 4.62 |
| 332.36 | 4.63 | 4.63 |
| 362.38 | 4.64 | 4.64 |
| 350.35 | 4.77 | 4.77 |
| 302.33 | 4.62 | 4.62 |
| 332.36 | 4.63 | 4.63 |
| 288.30 | 4.32 | 4.32 |
| 318.33 | 4.33 | 4.33 |
| 348.35 | 4.34 | 4.34 |
| 302.33 | 4.62 | 4.62 |
| 332.36 | 4.63 | 4.63 |
| 362.38 | 4.64 | 4.64 |
| 282.30 | 3.48 | 3.48 |
| 312.32 | 3.49 | 3.49 |