Basic Information
ID: ALA2423346
Type: ADME
Description: Time dependent inhibition of CYP3A4 in human liver microsomes using midazolam as substrate assessed as AUC shift of inhibition at 0.1 to 10 uM
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2423346
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.47 | 3.14 | 3.14 |
| 408.48 | 2.84 | 2.84 |
| 409.47 | 2.12 | 2.12 |
| 425.51 | 2.92 | 2.92 |
| 456.57 | 1.94 | 1.94 |
| 484.62 | 2.72 | 2.72 |