Basic Information
ID: ALA2423444
Type: Functional
Description: Antiproliferative activity against human HeLa cells assessed as cell survival ratio at 0.1 uM treated 1 hr before 2Gy ionizing radiation measured after 6 to 8 days by DMR clonogenic assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: HeLa(ALA399)
Document: ALA2417539
Antiproliferative activity against human HeLa cells assessed as cell survival ratio at 0.1 uM treated 1 hr before 2Gy ionizing radiation measured after 6 to 8 days by DMR clonogenic assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2423444
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.50 | 5.66 | 5.66 |
| 582.73 | 5.24 | 5.24 |
| 583.75 | 6.07 | 6.07 |
| 574.66 | 4.17 | 4.17 |
| 543.65 | 4.46 | 4.46 |
| 554.67 | 6.06 | 6.06 |
| 569.68 | 4.82 | 4.82 |
| 583.71 | 5.21 | 5.21 |
| 571.70 | 5.06 | 5.06 |
| 584.69 | 5.68 | 5.68 |
| 597.69 | 4.73 | 4.73 |
| 577.66 | 5.75 | 5.75 |
| 597.74 | 5.60 | 5.60 |
| 588.64 | 3.69 | 3.69 |
| 557.63 | 3.99 | 3.99 |
| 626.78 | 5.26 | 5.26 |
| 656.80 | 4.62 | 4.62 |
| 596.75 | 5.63 | 5.63 |
| 645.78 | 6.21 | 6.21 |
| 662.79 | 6.95 | 6.95 |
| 646.77 | 5.61 | 5.61 |
| 639.82 | 5.17 | 5.17 |
| 610.78 | 6.07 | 6.07 |
| 612.75 | 4.60 | 4.60 |
| 626.78 | 4.99 | 4.99 |
| 626.78 | 5.31 | 5.31 |
| 590.70 | 6.18 | 6.18 |
| 610.78 | 6.02 | 6.02 |
| 542.66 | 5.38 | 5.38 |
| 540.69 | 6.53 | 6.53 |
| 555.70 | 5.29 | 5.29 |
| 569.73 | 5.68 | 5.68 |
| 585.73 | 4.97 | 4.97 |
| 570.71 | 6.15 | 6.15 |
| 583.71 | 5.21 | 5.21 |
| 500.62 | 5.60 | 5.60 |
| 549.65 | 6.55 | 6.55 |
| 596.75 | 5.63 | 5.63 |
| 581.74 | 6.87 | 6.87 |
| 619.74 | 6.79 | 6.79 |
| 555.70 | 6.33 | 6.33 |
| 499.59 | 4.95 | 4.95 |
| 612.75 | 4.91 | 4.91 |
| 583.71 | 5.76 | 5.76 |
| 610.78 | 6.07 | 6.07 |
| 584.74 | 5.49 | 5.49 |
| 597.74 | 6.10 | 6.10 |
| 618.76 | 6.91 | 6.91 |
| 611.72 | 4.61 | 4.61 |
| 610.78 | 6.07 | 6.07 |
| 557.67 | 5.23 | 5.23 |
| 610.74 | 5.16 | 5.16 |
| 631.76 | 5.82 | 5.82 |
| 648.76 | 6.56 | 6.56 |
| 667.83 | 4.79 | 4.79 |
| 625.80 | 4.78 | 4.78 |
| 596.75 | 5.68 | 5.68 |
| 598.73 | 4.21 | 4.21 |
| 612.75 | 4.60 | 4.60 |
| 612.75 | 4.91 | 4.91 |
| 568.70 | 4.90 | 4.90 |
| 513.62 | 5.16 | 5.16 |
| 576.68 | 5.79 | 5.79 |
| 596.75 | 5.63 | 5.63 |
| 569.68 | 5.33 | 5.33 |
| 567.71 | 6.48 | 6.48 |
| 568.70 | 4.90 | 4.90 |
| 582.73 | 5.24 | 5.24 |
| 587.70 | 4.28 | 4.28 |
| 543.65 | 4.58 | 4.58 |
| 542.66 | 4.54 | 4.54 |
| 555.66 | 4.94 | 4.94 |
| 553.68 | 6.09 | 6.09 |
| 554.67 | 4.51 | 4.51 |
| 568.70 | 4.85 | 4.85 |
| 573.67 | 3.89 | 3.89 |
| 601.73 | 5.20 | 5.20 |
| 529.62 | 4.18 | 4.18 |
| 528.63 | 4.15 | 4.15 |
| 582.73 | 5.24 | 5.24 |
| 567.71 | 6.48 | 6.48 |
| 605.72 | 6.40 | 6.40 |
| 541.67 | 5.94 | 5.94 |
| 485.57 | 4.56 | 4.56 |
| 598.72 | 4.52 | 4.52 |
| 569.68 | 5.37 | 5.37 |
| 596.75 | 5.68 | 5.68 |
| 570.72 | 5.10 | 5.10 |
| 583.71 | 5.71 | 5.71 |
| 604.73 | 6.52 | 6.52 |
| 597.70 | 4.22 | 4.22 |
| 596.75 | 5.68 | 5.68 |
| 543.65 | 4.84 | 4.84 |
| 596.71 | 4.77 | 4.77 |
| 612.75 | 4.87 | 4.87 |
| 642.78 | 4.23 | 4.23 |