Basic Information
ID: ALA2423657
Type: Binding
Description: Inhibition of APE-1 (unknown origin) using double-stranded AP-site containing DNA as substrate after 30 mins by fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2423657
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.74 | 2.83 | 2.83 |
| 323.74 | 2.83 | 2.83 |
| 227.22 | 0.73 | 0.73 |
| 289.29 | 2.18 | 2.18 |
| 207.19 | -1.32 | -1.32 |
| 337.26 | 1.06 | 1.06 |
| 235.25 | -0.67 | -0.67 |
| 303.71 | 0.69 | 0.69 |
| 283.29 | -0.04 | -0.04 |
| 283.29 | 0.35 | 0.35 |
| 283.29 | 0.35 | 0.35 |
| 269.26 | 0.04 | 0.04 |
| 311.35 | 1.09 | 1.09 |
| 329.32 | 0.06 | 0.06 |
| 330.30 | 1.76 | 1.76 |
| 344.33 | 1.54 | 1.54 |
| 344.33 | 2.06 | 2.06 |
| 344.33 | 2.06 | 2.06 |
| 360.33 | 1.76 | 1.76 |
| 332.29 | 2.19 | 2.19 |
| 393.20 | 2.81 | 2.81 |
| 329.32 | 1.63 | 1.63 |
| 371.36 | 1.08 | 1.08 |
| 407.41 | 1.42 | 1.42 |
| 382.40 | 1.55 | 1.55 |
| 416.85 | 2.20 | 2.20 |
| 393.38 | 0.70 | 0.70 |
| 354.33 | 1.93 | 1.93 |
| 354.33 | 1.93 | 1.93 |
| 382.34 | 1.23 | 1.23 |
| 411.44 | 1.79 | 1.79 |
| 283.29 | 0.64 | 0.64 |
| 310.36 | 1.69 | 1.69 |
| 296.33 | 1.26 | 1.26 |
| 274.31 | 0.69 | 0.69 |
| 269.26 | -0.23 | -0.23 |
| 195.23 | -1.47 | -1.47 |
| 477.54 | 4.36 | 4.36 |
| 467.48 | 4.30 | 4.30 |
| 417.51 | 3.79 | 3.79 |
| 417.51 | 3.79 | 3.79 |
| 337.77 | 2.89 | 2.89 |
| 337.77 | 3.14 | 3.14 |
| 337.77 | 2.84 | 2.84 |
| 323.74 | 2.83 | 2.83 |
| 323.74 | 2.83 | 2.83 |
| 261.67 | 1.38 | 1.38 |
| 287.71 | 2.18 | 2.18 |
| 329.79 | 3.35 | 3.35 |
| 330.78 | 1.77 | 1.77 |
| 339.74 | 2.54 | 2.54 |
| 353.77 | 2.84 | 2.84 |
| 339.74 | 2.54 | 2.54 |
| 339.74 | 2.54 | 2.54 |
| 357.29 | 3.20 | 3.20 |
| 314.30 | 2.05 | 2.05 |
| 330.30 | 1.76 | 1.76 |
| 323.36 | 1.40 | 1.40 |
| 325.37 | 1.48 | 1.48 |
| 337.38 | 1.48 | 1.48 |
| 359.39 | 2.06 | 2.06 |
| 373.42 | 2.11 | 2.11 |
| 283.29 | 0.59 | 0.59 |
| 359.39 | 2.06 | 2.06 |
| 373.42 | 2.11 | 2.11 |
| 233.23 | -0.75 | -0.75 |
| 261.29 | 0.03 | 0.03 |
| 275.31 | 0.42 | 0.42 |
| 277.28 | -0.73 | -0.73 |
| 297.32 | 0.16 | 0.16 |
| 319.32 | 1.19 | 1.19 |
| 276.28 | -0.50 | -0.50 |
| 289.32 | 0.41 | 0.41 |
| 354.19 | 0.86 | 0.86 |
| 351.39 | 1.77 | 1.77 |
| 297.32 | 0.60 | 0.60 |
| 353.26 | 0.94 | 0.94 |
| 283.29 | 0.35 | 0.35 |