Basic Information
ID: ALA2423680
Type: Binding
Description: Inhibition of C-terminal His-tagged NAMPT (unknown origin) expressed in Escherichia coli BL21 using nicotinamide as substrate preincubated for 15 mins before substrate addition measured after 30 mins by mass spectrometry-based assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2423680
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.87 | 4.21 | 4.21 |
| 391.52 | 3.93 | 3.93 |
| 391.45 | 3.33 | 3.33 |
| 392.44 | 3.59 | 3.59 |
| 409.44 | 3.46 | 3.46 |
| 427.43 | 3.60 | 3.60 |
| 427.43 | 3.60 | 3.60 |
| 392.44 | 2.72 | 2.72 |
| 477.55 | 2.56 | 2.56 |
| 428.42 | 3.87 | 3.87 |
| 460.43 | 4.61 | 4.61 |
| 478.53 | 2.82 | 2.82 |
| 444.48 | 4.34 | 4.34 |
| 476.50 | 5.08 | 5.08 |
| 494.60 | 3.29 | 3.29 |
| 427.43 | 3.38 | 3.38 |
| 459.45 | 4.12 | 4.12 |
| 477.55 | 2.33 | 2.33 |
| 428.42 | 2.77 | 2.77 |
| 460.44 | 3.51 | 3.51 |
| 478.53 | 1.72 | 1.72 |
| 398.49 | 2.44 | 2.44 |
| 398.49 | 2.44 | 2.44 |
| 399.48 | 1.83 | 1.83 |
| 392.44 | 2.49 | 2.49 |
| 392.44 | 2.49 | 2.49 |
| 392.44 | 2.49 | 2.49 |
| 402.48 | 4.00 | 4.00 |
| 402.48 | 4.00 | 4.00 |
| 403.46 | 3.39 | 3.39 |
| 418.48 | 3.23 | 3.23 |
| 419.46 | 3.50 | 3.50 |
| 405.48 | 3.63 | 3.63 |
| 405.48 | 3.63 | 3.63 |
| 459.45 | 4.34 | 4.34 |
| 459.45 | 4.34 | 4.34 |
| 459.45 | 4.34 | 4.34 |
| 409.44 | 3.46 | 3.46 |
| 392.44 | 2.72 | 2.72 |
| 405.48 | 3.34 | 3.34 |
| 405.48 | 3.34 | 3.34 |
| 391.45 | 3.33 | 3.33 |
| 399.47 | 2.93 | 2.93 |
| 399.47 | 2.93 | 2.93 |
| 415.54 | 3.40 | 3.40 |
| 408.50 | 4.06 | 4.06 |
| 415.54 | 3.40 | 3.40 |
| 415.54 | 3.40 | 3.40 |
| 408.50 | 4.06 | 4.06 |
| 409.49 | 3.45 | 3.45 |
| 415.54 | 3.40 | 3.40 |
| 398.49 | 2.67 | 2.67 |
| 398.49 | 2.44 | 2.44 |
| 391.45 | 3.10 | 3.10 |
| 391.45 | 3.10 | 3.10 |
| 384.46 | 2.99 | 2.99 |
| 398.49 | 2.67 | 2.67 |
| 412.52 | 3.23 | 3.23 |
| 405.48 | 3.37 | 3.37 |
| 398.49 | 2.67 | 2.67 |