Basic Information
ID: ALA2426829
Type: Functional
Description: Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assay relative to glutamate
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Metabotropic glutamate receptor 5(ALA3227)
Document: ALA2424640
Positive allosteric modulation of human mGluR5a transfected in HEK293 cells by calcium mobilization assay relative to glutamate: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2426829
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 364.41 | 4.66 | 4.66 |
| 369.37 | 4.03 | 4.03 |
| 254.28 | 3.23 | 3.23 |
| 248.28 | 3.05 | 3.05 |
| 254.28 | 3.23 | 3.23 |
| 268.27 | 2.87 | 2.87 |
| 254.31 | 1.83 | 1.83 |
| 268.34 | 2.17 | 2.17 |
| 314.41 | 3.13 | 3.13 |
| 358.46 | 3.15 | 3.15 |
| 354.41 | 4.06 | 4.06 |
| 372.40 | 4.20 | 4.20 |
| 372.40 | 4.20 | 4.20 |
| 372.40 | 4.20 | 4.20 |
| 372.40 | 4.20 | 4.20 |
| 337.40 | 3.32 | 3.32 |
| 337.40 | 3.32 | 3.32 |
| 337.40 | 3.32 | 3.32 |
| 355.39 | 3.46 | 3.46 |
| 355.39 | 3.46 | 3.46 |
| 312.39 | 2.19 | 2.19 |
| 274.35 | 2.35 | 2.35 |
| 354.41 | 4.06 | 4.06 |
| 274.35 | 2.35 | 2.35 |
| 288.37 | 2.74 | 2.74 |
| 302.40 | 3.13 | 3.13 |
| 318.40 | 2.37 | 2.37 |
| 300.38 | 2.88 | 2.88 |
| 253.33 | 3.06 | 3.06 |