Assay Report Card

Basic Information

ID: ALA2426861

Type: Binding

Description: Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as [1,2,6,7-3H]-cortisol oxidation to [1,2-3H]-cortisone at 20 uM after 10 mins in presence of NAD+

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
399.523.643.64
373.503.123.12
320.402.832.83
356.452.382.38
356.452.082.08
370.482.392.39
412.563.383.38
386.482.092.09
416.502.102.10
431.472.002.00
400.461.781.78
400.461.781.78
415.481.201.20
415.481.201.20