Basic Information
ID: ALA2426862
Type: Binding
Description: Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [1,2-3H]-cortisone reduction to [1,2,6,7-3H]-cortisol after 10 mins in presence of NADPH
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2426862
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 399.52 | 3.64 | 3.64 |
| 373.50 | 3.12 | 3.12 |
| 320.40 | 2.83 | 2.83 |
| 356.45 | 2.38 | 2.38 |
| 356.45 | 2.08 | 2.08 |
| 370.48 | 2.39 | 2.39 |
| 412.56 | 3.38 | 3.38 |
| 386.48 | 2.09 | 2.09 |
| 416.50 | 2.10 | 2.10 |
| 431.47 | 2.00 | 2.00 |
| 400.46 | 1.78 | 1.78 |
| 400.46 | 1.78 | 1.78 |
| 415.48 | 1.20 | 1.20 |
| 415.48 | 1.20 | 1.20 |