Assay Report Card

Basic Information

ID: ALA2426864

Type: Binding

Description: Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [1,2-3H]-cortisone reduction to [1,2,6,7-3H]-cortisol measured as residual activity at 20 uM after 10 mins relative to control in presence of NADPH

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
373.503.123.12
320.402.832.83
356.452.382.38
400.461.781.78
400.461.781.78
415.481.201.20
415.481.201.20