Basic Information
ID: ALA2426870
Type: ADME
Description: Prodrug activation in APP51/16 transgenic male mouse blood assessed as (1R,3R,4S,5S)-3-Amino-5-[4-amino-3-fluoro-5-((R)-2,2,2-trifluoro-1-methoxymethyl-ethoxy)-benzyl]-1-oxo-tetrahydro-thiopyran-4-ol level at 60 umol/kg, po after 4 hrs
Format: BAO_0000218
Organism: Mus musculus
Tissue: Blood
Target: Blood(ALA613561)
Document: ALA2424550
Prodrug activation in APP51/16 transgenic male mouse blood assessed as (1R,3R,4S,5S)-3-Amino-5-[4-amino-3-fluoro-5-((R)-2,2,2-trifluoro-1-methoxymethyl-ethoxy)-benzyl]-1-oxo-tetrahydro-thiopyran-4-ol level at 60 umol/kg, po after 4 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2426870
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.60 | 4.09 | 4.09 |
| 560.65 | 4.10 | 4.10 |
| 562.67 | 4.10 | 4.10 |