Basic Information
ID: ALA2427031
Type: ADME
Description: Prodrug activation in APP51/16 transgenic male mouse blood assessed as (1R,3S,4S,5R)-3-(4-Amino-3-fluoro-5-hydroxy-benzyl)-5-(3-tert-butyl-benzylamino)-1-oxo-tetrahydro-thiopyran-4-ol level at 60 umol/kg, po after 4 hrs
Format: BAO_0000218
Organism: Mus musculus
Tissue: Blood
Target: Blood(ALA613561)
Document: ALA2424550
Prodrug activation in APP51/16 transgenic male mouse blood assessed as (1R,3S,4S,5R)-3-(4-Amino-3-fluoro-5-hydroxy-benzyl)-5-(3-tert-butyl-benzylamino)-1-oxo-tetrahydro-thiopyran-4-ol level at 60 umol/kg, po after 4 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2427031
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 516.60 | 4.09 | 4.09 |
| 560.65 | 4.10 | 4.10 |
| 562.67 | 4.10 | 4.10 |